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Study identifier: NCT06075771 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Dopaminergic Therapy for Anhedonia - 2

Condition: Anhedonia · Depression  ·  Sponsor: Emory University

PhasePhase 4
Planned participants70
Who can joinAll sexes, 25 Years to 55 Years
Healthy volunteersNo

About this study

The purpose of this 8-week, double-blind, placebo-controlled, study is to explore new treatment options for people with depression who have high inflammation and anhedonia. Seventy male and female participants with depression, between 25-55 years of age, with higher levels of inflammation and anhedonia will be randomized to receive L-DOPA or matched placebo over 8 weeks. Participants will complete lab tests, medical and psychiatric assessments, motivation and motor tasks, and MRI scans as part of the study. The total length of participation is approximately 10 to 12 weeks.

This description comes directly from the study's public registry record.

Talk to the study team

Jennifer Felger, PhD  ·  4047273987  ·  jfelger@emory.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Emory University HospitalAtlanta, Georgia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06075771