Condition: Hematopoietic Organs; Disorder · Sponsor: Hong Kong Children's Hospital
In this comparative study, the investigators aim to compare prospective pediatric patients who receive total lymphoid irradiation (TLI) using tomotherapy with age- and disease-matched controls who receive conventional total body irradiation (TBI) as part of conditioning for haploidentical hematopoietic stem cell transplantation (HSCT) for both malignant and non-malignant diseases. The investigators shall evaluate graft failure-free, graft-versus-host disease (GVHD)-free survival, overall survival, frequency of rejection, GVHD, relapse of malignancy, adverse effects and post-transplant immunoreconstitution.
This description comes directly from the study's public registry record.
Daniel Cheuk · 852-35136049 · cheukkld@gmail.com
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| Hong Kong Children's Hospital | Hong Kong, Hong Kong | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06075563