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Study identifier: NCT06072924 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

K01 Impacts of Lingual Endurance Exercise

Condition: Dysphagia · Dysphagia, Oropharyngeal · Ischemic Stroke  ·  Sponsor: University of Cincinnati

PhaseNA
Planned participants70
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn whether a tongue endurance exercise program can improve swallowing function in adults with dysphagia after a stroke. It also aims to explore how this exercise may affect brain structure and connectivity involved in swallowing. The main questions it aims to answer are: Primary Aim: Does lingual endurance exercise improve swallowing function compared to a sham therapy? Secondary Aim: Does lingual endurance exercise lead to changes in brain structure or neuroplasticity, as measured by MRI? Researchers will compare a group receiving tongue endurance exercises to a sham therapy group to see whether the treatment improves tongue function, swallowing. Participants will: * Complete a baseline swallowing assessment and MRI * Be randomly assigned to either the lingual exercise or sham therapy group * Complete 8 weeks of home-based tongue exercise therapy * Return for follow-up swallowing assessments * A subgroup of participants will complete a pre-treatment and post-treatment MRI.

This description comes directly from the study's public registry record.

Talk to the study team

Anna Hopkins, MS  ·  +1 513 558 4152  ·  hopkiak@ucmail.uc.edu

Rebecca Reinert  ·  +1 513 558 1719  ·  gibsonrk@ucmail.uc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of CincinnatiCincinnati, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06072924