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Study identifier: NCT06071845 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples

Condition: Barrett Esophagus · Barretts Esophagus With Dysplasia · Barrett's Esophagus Without Dysplasia  ·  Sponsor: Mayo Clinic

PhaseNA
Planned participants450
Who can joinAll sexes, 18 Years to 90 Years
Healthy volunteersNo

About this study

This clinical trial evaluates the use of cytosponge, a minimally invasive collection device, for the detection of Barrett's esophagus (BE) in patients undergoing endoscopy. Non-endoscopic swallowable encapsulate sponge cell collection devices combined with markers for BE/esophageal adenocarcinoma (EAC) detection are a guideline-endorsed alternative to endoscopy for BE screening. The Oncoguard registered trademark Esophagus test (OGE) test uses esophageal cytology specimens collected with a minimally invasive, non-endoscopic, encapsulated sponge sampling device to identify BE/EAC biomarkers that indicate whether a patient should undergo diagnostic endoscopy. The OGE test is a simple and cost effective screening method that may lower barriers to widespread adoption of BE screening in at risk patients, resulting in increased and earlier detection of BE/EAC.

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trials Referral Office  ·  855-776-0015  ·  mayocliniccancerstudies@mayo.edu

Always discuss trial participation with your own doctor first.

Locations (5)

Mayo ClinicScottsdale, Arizona, United StatesRecruiting
Mayo Clinic in FloridaJacksonville, Florida, United StatesRecruiting
Northwestern UniversityChicago, Illinois, United StatesTerminated
Mayo Clinic in RochesterRochester, Minnesota, United StatesRecruiting
Long Island Jewish Medical Center | Northwell HealthNew Hyde Park, New York, United StatesCompleted

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Source record: clinicaltrials.gov/study/NCT06071845