Condition: HIV-1-infection · Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
The purpose of this study is to evaluate the safety, tolerability, and efficacy of therapeutic vaccination with chimpanzee adenovirus ChAdOx1- and poxvirus modified vaccinia Ankara (MVA)-vectored conserved mosaic T-cell vaccines in a sequential regimen with the toll-like receptor 7 (TLR7) agonist vesatolimod (VES) and two broadly neutralizing antibodies (bNAbs) compared to placebo, to induce HIV-1 control during analytic treatment interruption (ATI).
This description comes directly from the study's public registry record.
Contact details are listed per location below or on the registry record.
Always discuss trial participation with your own doctor first.
| University of California, San Diego AntiViral Research Center CRS | San Diego, California, United States | Recruiting |
| Ponce de Leon Center CRS | Atlanta, Georgia, United States | Recruiting |
| Northwestern University CRS | Chicago, Illinois, United States | Recruiting |
| Massachusetts General Hospital CRS (MGH CRS) | Boston, Massachusetts, United States | Not Yet Recruiting |
| Washington University Therapeutics CRS | St Louis, Missouri, United States | Recruiting |
| Columbia Physicians & Surgeons CRS | New York, New York, United States | Recruiting |
| Chapel Hill CRS | Chapel Hill, North Carolina, United States | Recruiting |
| Ohio State University CRS | Columbus, Ohio, United States | Recruiting |
| Penn Therapeutics CRS | Philadelphia, Pennsylvania, United States | Recruiting |
| Houston AIDS Research Team CRS | Houston, Texas, United States | Recruiting |
| Instituto de Pesquisas em AIDS do Rio Grande do Sul - IPARGS CRS | Porto Alegre, Rio Grande do Sul, Brazil | Recruiting |
| Instituto de Pesquisa Clinica Evandro Chagas (IPEC) CRS | Rio de Janeiro, Brazil | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT06071767