Condition: Stage IV Periodontitis · Orthodontic Tooth Movement · Sponsor: Universidad Complutense de Madrid
Micro-osteoperforations (MOPs) cause cortical bone injuries and consequently increase the expression of inflammatory mediators, allowing for increased bone and periodontal ligament remodeling associated with orthodontic movement. It remains unclear the effect of orthodontic intrusion combined with MOPs application on teeth with reduced periodontium. The general objective will be to determine the efficacy of MOPs during orthodontic tooth movement (OTM) in terms of periodontal and orthodontic outcomes in stage IV periodontitis patients, case type 2 with pathological tooth migration (PTM), characterized the presence of at least one flared tooth of the upper-anterior sextant with an intrabony defect (intrabony component \<5mm)
This description comes directly from the study's public registry record.
Conchita Martin, Prof · +343941901 · mariacom@ucm.es
Elena Figuero, Prof · +343941901 · efigueruiz@odon.ucm.es
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| Faculty of Odontology, University Complutense Madrid | Madrid, Madrid, Spain | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06068270