Condition: Metastatic Cancer · Breast Cancer · Lobular Breast Carcinoma · Sponsor: University of Wisconsin, Madison
This pilot observational study is being done to identify possible biomarkers of response to endocrine therapy in patients with ER/PR+ metastatic lobular breast cancer (LBC) starting new endocrine therapy. 18F-fluorofuranylnorprogesterone Positron Emission Tomography/Computed Tomography (FFNP-PET/CT) and liquid biopsies will be performed at baseline and after 4 weeks of treatment. Baseline levels and dynamic on-treatment changes in estrogen signaling as measured by FFNP-PET/CT and circulating tumor cell (CTC) liquid biopsy will be correlated with clinical response to endocrine therapy and progression-free survival in the above cohort of patients.
This description comes directly from the study's public registry record.
Cancer Connect · 800-622-8922 · clinicaltrials@cancer.wisc.edu
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| UW Carbone Cancer Center | Madison, Wisconsin, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06067503