Condition: Small Bowel Obstruction · Sponsor: University Hospital, Angers
For uncomplicated acute small bowel obstruction (aSBO), the "Bologna guidelines" recommend non-surgical management of 72 hours before considering surgery. This treatment is based on the placement of a nasogastric tube and the correction of hydro-electrolyte disorders. Non-surgical management is only effective in 60 to 70% and surgery is therefore necessary in 30 to 40% of cases after medical treatment for at least 3 days. This therefore leads to an increase in the length of hospital stay. Some authors also point out that postponing surgery for 3 days would aggravate the morbidity and mortality of surgery. Indeed, aSBO surgery has a complication rate of 10-40% and a mortality of up to 4%. There is a lack of studies evaluating what is the best management strategy for aSBO, especially with regard to the duration of medical treatment. Many recent studies plead in favor of early surgical treatment (\<24 hours) which would reduce the morbidity and mortality rate of surgery but also the overall cost of treatment by reducing the length of stay. This paradigm shift is linked to the improvement of anesthetic and intensive care management over the last few years, but also to the advent of laparoscopy in emergency surgery. Indeed, laparoscopy could reduce the duration of hospitalization but also the operative morbidity and mortality. However, this surgical approach is not feasible in all situations and the conversion rate is reported in 30 to 76% of cases. One of the factors favoring t…
This description comes directly from the study's public registry record.
Paul Le Naoures, Dr · (0)2 41 35 49 16 · Paul.LeNaoures@chu-angers.fr
Aurélien Vénara, Pr · (0)2 41 35 36 18 · AuVenara@chu-angers.fr
Always discuss trial participation with your own doctor first.
| University Hospital of Amiens | Amiens, France | Not Yet Recruiting |
| University Hospital of Angers | Angers, France | Recruiting |
| University Hospital of Brest | Brest, France | Not Yet Recruiting |
| University Hospital of Tours | Chambray-lès-Tours, France | Recruiting |
| Hospital of Haut Anjou | Château-Gontier, France | Not Yet Recruiting |
| University Hospital of Dijon Bourgogne | Dijon, France | Not Yet Recruiting |
| University Hospital of Grenoble-Alpes | Grenoble, France | Recruiting |
| Hospital of Vendée | La Roche-sur-Yon, France | Recruiting |
| University Hospital of Montpellier | Montpellier, France | Not Yet Recruiting |
| University Hospital of Nantes | Nantes, France | Not Yet Recruiting |
| University Hospital of Nice | Nice, France | Not Yet Recruiting |
| University Hospital of Lyon | Pierre-Bénite, France | Not Yet Recruiting |
+ 2 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT06065150