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Study identifier: NCT06065150 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Early Surgery Versus 3 Days Non-surgical Management in Acute Small Bowel Obstruction (SURGI-BOW)

Condition: Small Bowel Obstruction  ·  Sponsor: University Hospital, Angers

PhaseNA
Planned participants630
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

For uncomplicated acute small bowel obstruction (aSBO), the "Bologna guidelines" recommend non-surgical management of 72 hours before considering surgery. This treatment is based on the placement of a nasogastric tube and the correction of hydro-electrolyte disorders. Non-surgical management is only effective in 60 to 70% and surgery is therefore necessary in 30 to 40% of cases after medical treatment for at least 3 days. This therefore leads to an increase in the length of hospital stay. Some authors also point out that postponing surgery for 3 days would aggravate the morbidity and mortality of surgery. Indeed, aSBO surgery has a complication rate of 10-40% and a mortality of up to 4%. There is a lack of studies evaluating what is the best management strategy for aSBO, especially with regard to the duration of medical treatment. Many recent studies plead in favor of early surgical treatment (\<24 hours) which would reduce the morbidity and mortality rate of surgery but also the overall cost of treatment by reducing the length of stay. This paradigm shift is linked to the improvement of anesthetic and intensive care management over the last few years, but also to the advent of laparoscopy in emergency surgery. Indeed, laparoscopy could reduce the duration of hospitalization but also the operative morbidity and mortality. However, this surgical approach is not feasible in all situations and the conversion rate is reported in 30 to 76% of cases. One of the factors favoring t…

This description comes directly from the study's public registry record.

Talk to the study team

Paul Le Naoures, Dr  ·  (0)2 41 35 49 16  ·  Paul.LeNaoures@chu-angers.fr

Aurélien Vénara, Pr  ·  (0)2 41 35 36 18  ·  AuVenara@chu-angers.fr

Always discuss trial participation with your own doctor first.

Locations (14)

University Hospital of AmiensAmiens, FranceNot Yet Recruiting
University Hospital of AngersAngers, FranceRecruiting
University Hospital of BrestBrest, FranceNot Yet Recruiting
University Hospital of ToursChambray-lès-Tours, FranceRecruiting
Hospital of Haut AnjouChâteau-Gontier, FranceNot Yet Recruiting
University Hospital of Dijon BourgogneDijon, FranceNot Yet Recruiting
University Hospital of Grenoble-AlpesGrenoble, FranceRecruiting
Hospital of VendéeLa Roche-sur-Yon, FranceRecruiting
University Hospital of MontpellierMontpellier, FranceNot Yet Recruiting
University Hospital of NantesNantes, FranceNot Yet Recruiting
University Hospital of NiceNice, FranceNot Yet Recruiting
University Hospital of LyonPierre-Bénite, FranceNot Yet Recruiting

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06065150