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Study identifier: NCT06063850 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy

Condition: Mesial Temporal Lobe Epilepsy  ·  Sponsor: UniQure Biopharma B.V.

PhasePhase 1/Phase 2
Planned participants12
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The main goals of this clinical study are to learn if AMT-260 is safe and tolerable and works to reduce the frequency of seizures in adults with unilateral mesial temporal lobe epilepsy (MTLE).

This description comes directly from the study's public registry record.

Talk to the study team

uniQure  ·  1-866-520-1257  ·  medinfo@uniqure.com

Always discuss trial participation with your own doctor first.

Locations (18)

University of Alabama at BirminghamBirmingham, Alabama, United StatesRecruiting
Mayo Clinic ArizonaPhoenix, Arizona, United StatesRecruiting
Stanford UniversityPalo Alto, California, United StatesRecruiting
Mayo Clinic FloridaJacksonville, Florida, United StatesRecruiting
Kansas University Medical CenterKansas City, Kansas, United StatesRecruiting
Johns Hopkins School of MedicineBaltimore, Maryland, United StatesRecruiting
Midatlantic Epilepsy and Sleep CenterBethesda, Maryland, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
Corewell HealthGrand Rapids, Michigan, United StatesRecruiting
Dartmouth Hitchcock Medical CenterLebanon, New Hampshire, United StatesRecruiting
Northeast Regional Epilepsy GroupHackensack, New Jersey, United StatesRecruiting
Robert Wood Johnson HospitalNew Brunswick, New Jersey, United StatesRecruiting

+ 6 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06063850