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Study identifier: NCT06062823 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of EGFR TKI in Patients With Advanced NSCLC Harbouring EGFR Mutations

Condition: NSCLC  ·  Sponsor: National University Hospital, Singapore

PhasePhase 2
Planned participants35
Who can joinAll sexes, 21 Years to 99 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to explore the efficacy of afatinib in NSCLC harbouring EGFR PACC mutation subtype. The main question it aims to answer is: Afatinib is active in patients with advanced NSCLC harbouring EGFR PACC mutation subtype. Participants will undergo screening, follow by treatment if eligible for study participation and then enter follow up phase after study medication has stopped. Patients will take afatinib 40mg daily continuously, until the development of progressive disease or meeting discontinuation criteria. A treatment cycle is defined as 28 days.

This description comes directly from the study's public registry record.

Talk to the study team

Kenneth Sooi  ·  +65 6908 2222  ·  kenneth_sooi@nuhs.edu.sg

Always discuss trial participation with your own doctor first.

Locations (1)

National University HospitalSingapore, SingaporeRecruiting

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Source record: clinicaltrials.gov/study/NCT06062823