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Study identifier: NCT06059664 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The EFfect of FinErenone in Kidney TransplantiOn Recipients: The EFFEKTOR Study

Condition: Kidney Transplant; Complications  ·  Sponsor: University of North Carolina, Chapel Hill

PhasePhase 2
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

EFFEKTOR is a vanguard, multicenter, phase 2 randomized, double blinded, placebo controlled clinical trial to determine the feasibility, tolerability, safety, and efficacy of finerenone in kidney transplant recipients (KTRs). One hundred fifty (150) KTRs will be randomized in a 2:1 ratio of finerenone to placebo, with two embedded substudies: (i) a kidney biopsy substudy in 50 participants who undergo a research kidney biopsy prior to randomization and at the end of active treatment; and (ii) a functional MRI (fMRI) substudy in 50 participants who undergo fMRI prior to randomization and at the end of active treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Amy Mottl, MD, MPH  ·  919-445-2641  ·  amy_mottl@med.unc.edu

Sara Kelley, MPH  ·  919-445-2658  ·  sara_kelley@med.unc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UNC Eastowne Kidney Transplant ClinicChapel Hill, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06059664