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Study identifier: NCT06059495 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Watch-and-Wait Approach With Dostarlimab in Localized dMMR/MSI-H Gastric Cancer: GERCOR Phase II Study

Condition: Adenocarcinoma - GEJ · Gastric Adenocarcinoma  ·  Sponsor: GERCOR - Multidisciplinary Oncology Cooperative Group

PhasePhase 2
Planned participants59
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This phase II study will evaluate dostarlimab with a watch-and-wait approach for patients with localized mismatch repair deficiency (dMMR)/microsatellite instability (MSI) gastric or oeso-gastric junction adenocarcinoma. The goal of the study is to determine whether the surgery could be avoided in patients with localized dMMR/MSI-H gastric/OGJ adenocarcinoma with complete response at endoscopy and biopsies free of tumoral cells after treatment with dostarlimab, with a watch-and-wait approaches.

This description comes directly from the study's public registry record.

Talk to the study team

Marie-Line GARCIA LARNICOL, MD  ·  +33 (01) 40 20 85 00  ·  gercor@gercor.com.fr

Always discuss trial participation with your own doctor first.

Locations (2)

CHRU LilleLille, FranceRecruiting
Hôpital Saint AntoineParis, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06059495