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Study identifier: NCT06059118 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer

Condition: Prostate Cancer  ·  Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

PhasePhase 2
Planned participants50
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Asymptomatic patients with metastatic castrate resistant prostate cancer (mCRPC) without pain due to prostate cancer will be treated on an open label study to evaluate effectiveness of sequential treatment with the combination of difluoromethylornithine (DFMO) and high dose testosterone in sequence with enzalutamide to improve primary and secondary outcomes.

This description comes directly from the study's public registry record.

Talk to the study team

Laura Sena, MD, PhD  ·  410-502-3825  ·  laura.sena@jhmi.edu

Kathy Schultz, RN  ·  410-614-9482  ·  kschult3@jhmi.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Johns Hopkins University: Sidney Kimmel Comprehensive Cancer CenterBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06059118