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Study identifier: NCT06055452 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effects of SGLT2 Inhibitors in Pre-heart Failure Populations With Hypertension

Condition: Pre-Heart Failure · Hypertension  ·  Sponsor: China National Center for Cardiovascular Diseases

PhasePhase 4
Planned participants120
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

In this multicenter, randomized, placebo-controlled trial in pre-heat failure patients with hypertension and without diabetes, we will enroll 120 eligible patients to randomized to receive placebo or engagliflozin (10mg/d) for follow them for 6 months. The primary endpoint is the left atrial volume index, which reflects left ventricular diastolic function. We sought to comprehensively evaluate the effect of engagliflozin on the structure and function and explore its underlying mechanisms.

This description comes directly from the study's public registry record.

Talk to the study team

Xin Zheng, MD,PhD  ·  +86 13681077247  ·  zhengxin@fuwai.com

Always discuss trial participation with your own doctor first.

Locations (2)

Fuwai Hospital, Chinese Academy of Medical SciencesBeijing, Beijing Municipality, ChinaRecruiting
Fuwai Hospital Chinese Academy of Medial Sciences, ShenzhenShenzhen, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06055452