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Study identifier: NCT06051240 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Lithium Treatment to Prevent Cognitive Impairment After Brain Radiotherapy

Condition: Cognitive Impairment · Cognitive Decline · Radiotherapy Side Effect  ·  Sponsor: Region Stockholm

PhasePhase 2
Planned participants84
Who can joinAll sexes, 5 Years to no upper limit
Healthy volunteersNo

About this study

Randomized, placebo-controlled, double-blinded, parallel group clinical trial to investigate if 6 months of oral lithium tablets (S-lithium 0,5-1,0 mmol/l) will prevent cognitive decline after brain radiotherapy in pediatric brain tumor survivors. Primary outcome measure is Processing Speed Index (PSI) 2 years after start of study treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Klas Blomgren, MD, Professor  ·  0046703233353  ·  klas.blomgren@regionstockholm.se

Gustaf Hellspong, MD, PhD Student  ·  0707308144  ·  gustaf.hellspong@regionstockholm.se

Always discuss trial participation with your own doctor first.

Locations (2)

Karolinska UniversitetssjukhusetSolna, Stockholm County, SwedenNot Yet Recruiting
HOPEStockholm, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT06051240