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Study identifier: NCT06050603 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

MRI Guided Closed-loop TMS-EEG

Condition: Normal Physiology · Amnestic Mild Cognitive Impairment  ·  Sponsor: Sunnybrook Health Sciences Centre

PhaseNA
Planned participants160
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersYes

About this study

The goal of this interventional study is to develop an individualized approach using transcranial magnetic stimulation (TMS) in a high-precision manner. This approach will use TMS to modulate brain activity at multiple locations simultaneously. Functional magnetic resonance imaging (fMRI) and electroencephalograph (EEG) will record the responses and guide the stimulation. Specifically, the placement and orientation of TMS coils will be tailored to stimulate the targeted functional brain areas informed by fMRI. To maximize the interventional effect, stimulation pulses will be delivered based on EEG oscillations.

This description comes directly from the study's public registry record.

Talk to the study team

Fa-Hsuan Lin, PhD  ·  416-480-6100  ·  fhlin@sri.utoronto.ca

Hsin-Ju Lee, PhD  ·  416-480-6100  ·  hsinju.lee@utoronto.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Sunnybrook Health Sciences CentreToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06050603