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Study identifier: NCT06046118 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Photobiomodulation in Dry Age Related Macular Degeneration

Condition: Age-Related Macular Degeneration  ·  Sponsor: Azienda Ospedaliera Universitaria Mater Domini, Catanzaro

PhaseNA
Planned participants180
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate effects of consecutive Yellow and Red Light Emitting Diode photobiomodulation in dry age-related macular degeneration (AMD). The main questions it aims to answer are: * Is Yellow and Red Light Emitting Diode photobiomodulation effective in decreasing drusen volume in patients affected by dry AMD? * Does Yellow and Red Light Emitting Diode photobiomodulation increase visual acuity and contrast sensitivity in patients affected by dry AMD? Participants will be randomly assigned to a treatment or a sham group. Treatment consists in two cycles with two phases each: * 1st phase: 300 seconds of continuous Yellow light with eyes closed + 60 seconds of pulsed Yellow light with eyes opened; * 2d phase: 300 seconds of continuous Red light with eyes closed + 60 seconds of pulsed Red light with eyes opened. Cycle 1 consists of 8 sessions (two PBM per week for 4 weeks) and cycle 2 consists of 6 sessions (two PBM per week for 3 weeks). Researchers will compare patients in the treatment group to those in the sham group to evaluate differences in objective signs and subjective symptoms of dry AMD.

This description comes directly from the study's public registry record.

Talk to the study team

Giuseppe Giannaccare  ·  003909613647135  ·  giuseppe.giannaccare@unicz.it

Always discuss trial participation with your own doctor first.

Locations (7)

University of ParisParis, FranceRecruiting
Università degli Studi di FerraraFerrara, ItalyRecruiting
Università degli studi della Campania Luigi VanvitelliNaples, ItalyRecruiting
Università di TorinoTorino, ItalyRecruiting
University of AnkaraAnkara, Turkey (Türkiye)Recruiting
Koç University HospitalKoç, Turkey (Türkiye)Recruiting
Earlam and ChristopherTaunton, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06046118