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Study identifier: NCT06046040 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

TmPSMA-02 in mCRPC

Condition: Metastatic Castrate-Resistant Prostate Cancer (mCRPC)  ·  Sponsor: University of Pennsylvania

PhasePhase 1
Planned participants30
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase I, open-label dose finding study to assess the safety, tolerability, manufacturing feasibility, and preliminary efficacy of TmPSMA-02 CAR T cells in patients with metastatic castrate-resistant prostate cancer (mCRPC). Up to 4 total dose levels will be evaluated using a 3+3 dose escalation design.

This description comes directly from the study's public registry record.

Talk to the study team

Abramson Cancer Center Clinical Trials Service  ·  215-349-8245  ·  PMCancerResearch@pennmedicine.upenn.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Abramson Cancer Center of the University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06046040