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Study identifier: NCT06045754 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

Condition: Crohn's Disease  ·  Sponsor: Takeda

PhasePhase 4
Planned participants100
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with adalimumab or vedolizumab (VDZ) together with ustekinumab (UST) in adults with moderate to severe Crohn's Disease, and the effect of treatment with vedolizumab alone, after the dual targeted treatment. The study is conducted in two parts. In Part A, participants will receive the dual targeted treatment (vedolizumab together with either adalimumab or ustekinumab). In part B, participants will receive vedolizumab only. Part B will include participants who responded to the treatment in Part A. Each participant will be followed up for at least 26 weeks after the last dose of treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Takeda Contact  ·  +1-877-825-3327  ·  medinfoUS@takeda.com

Always discuss trial participation with your own doctor first.

Locations (53)

Digestive Health SpecialsitsDothan, Alabama, United StatesRecruiting
GI Alliance Sun CitySun City, Arizona, United StatesRecruiting
University of California San Diego Health (UCSD)La Jolla, California, United StatesRecruiting
Cedars-Sinai Medical CenterLos Angeles, California, United StatesRecruiting
Hoag Hospital Newport BeachNewport Beach, California, United StatesRecruiting
Medical Research Center of Connecticut, LLCHamden, Connecticut, United StatesRecruiting
Clinical Research of OsceolaKissimmee, Florida, United StatesActive Not Recruiting
Endoscopic Research IncOrlando, Florida, United StatesRecruiting
Alliance Clinical Research of Tampa, LLCTampa, Florida, United StatesRecruiting
Gastroenterology Consultants, P.C.Roswell, Georgia, United StatesRecruiting
University of Chicago MedicineChicago, Illinois, United StatesRecruiting
GI Alliance - Illinois Gastroenterology Group - GlenviewGlenview, Illinois, United StatesRecruiting

+ 41 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06045754