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Study identifier: NCT06045429 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Oral Care With 3% Hydrogen Peroxide (Oroxid®) in ICU - Effects on the Lower Airway Microbial Colonisation

Condition: VAP - Ventilator Associated Pneumonia  ·  Sponsor: Charles University, Czech Republic

PhasePhase 4
Planned participants160
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

HyPerMICROBE is a single-centre, controlled, randomised, prospective, superiority clinical trial to compare the efficacy of daily oral care with 3% hydrogen peroxide (Oroxid®) versus standard of care (0.2% chlorhexidine digluconate) on the cumulative incidence of lower respiratory tract microbial colonisation in mechanically ventilated adult critically ill patients.

This description comes directly from the study's public registry record.

Talk to the study team

Kateřina Rambousková, MD  ·  +420 721 185 134  ·  kacakoubkova@seznam.cz

Adela Jiroudkova  ·  +420 602 145 168  ·  adela.jiroudkova@ruk.cuni.cz

Always discuss trial participation with your own doctor first.

Locations (1)

3rd Faculty of Medicine and FNKVPrague, CzechiaRecruiting

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Source record: clinicaltrials.gov/study/NCT06045429