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Study identifier: NCT06044025 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy

Condition: Castration Sensitive Prostate Cancer  ·  Sponsor: University of Arkansas

PhasePhase 1
Planned participants34
Who can joinMale, 18 Years to 100 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to assess the feasibility of adding a combination of metformin and turmeric as part of a nutritional intervention regimen to the current standard of care, namely, intermittent Androgen Deprivation Therapy (iADT), for patients with castration sensitive biochemical progressive prostate cancer. The main objectives are: * Assess the feasibility of the study population and enrollment. * Evaluate time to PSA relapse with nutritional intervention on iADT. Participants who are receiving iADT will be dispensed Metformin and turmeric and complete a pill diary. Participants will also have blood and stool samples collected and complete quality of life questionnaires. The long-term goal is to further assess the efficacy and safety of this nutritional regimen and the roles of metabolic syndrome, microenvironment/microbiome, and genomic vs epigenomic profiles in the care of these patients through a clinical trial.

This description comes directly from the study's public registry record.

Talk to the study team

Madison Trujillo  ·  5016868274  ·  MTrujillo@uams.edu

Aaron Holley  ·  5016868274  ·  jaholley@uams.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Arkansas for Medical SciencesLittle Rock, Arkansas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06044025