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Study identifier: NCT06043427 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal Adenocarcinoma

Condition: Gastroesophageal Adenocarcinoma  ·  Sponsor: Canadian Cancer Trials Group

PhasePhase 2
Planned participants168
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is being done to answer the following question: Can the chance of gastroesophageal cancer growing or spreading be lowered by adding a drug called zanidatamab to the usual combination of drugs? We are doing this study because we want to find out if this approach is better or worse than the usual approach for this type of cancer. The usual approach is defined as care most people get for gastroesophageal cancer

This description comes directly from the study's public registry record.

Talk to the study team

Chris O'Callaghan  ·  613-533-6430  ·  cocallaghan@ctg.queensu.ca

Always discuss trial participation with your own doctor first.

Locations (18)

Arthur J.E. Child Comprehensive Cancer CentreCalgary, Alberta, CanadaRecruiting
BCCA - VancouverVancouver, British Columbia, CanadaRecruiting
CancerCare ManitobaWinnipeg, Manitoba, CanadaRecruiting
QEII Health Sciences CentreHalifax, Nova Scotia, CanadaRecruiting
Royal Victoria Regional Health CentreBarrie, Ontario, CanadaRecruiting
Juravinski Cancer Centre at Hamilton Health SciencesHamilton, Ontario, CanadaRecruiting
Kingston Health Sciences CentreKingston, Ontario, CanadaRecruiting
Waterloo Regional Health Network (WRHN)Kitchener, Ontario, CanadaRecruiting
London Health Sciences Centre Research Inc.London, Ontario, CanadaRecruiting
Lakeridge Health OshawaOshawa, Ontario, CanadaRecruiting
Ottawa Hospital Research InstituteOttawa, Ontario, CanadaRecruiting
Odette Cancer CentreToronto, Ontario, CanadaRecruiting

+ 6 more locations — full list on the registry record.

Follow this study

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Source record: clinicaltrials.gov/study/NCT06043427