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Study identifier: NCT06039176 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future

Condition: LVAD · Frailty · GI Bleed  ·  Sponsor: International Consortium of Circulatory Assist Clinicians

PhaseN/A
Planned participants150
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

About this study

Durable left ventricular assist devices (dLVAD) have been increasingly utilized since the mid to late 1990s, with an uptick of utility starting in 2010 following expanded indications for therapy to not only include a bridge to transplantation strategy, but also for those individuals who suffer from advanced heart failure (HF) and do not qualify for cardiac transplantation. Despite the decreasing size of the newest generation devices leading to a lessened occurrence of adverse events, bleeding and infection still remain a concern for clinicians, as well as a general lack of predictability towards adverse events in individuals with a dLVAD in place. There is a lack of description in the literature currently, regarding the interface between what the pump data provides and what is seen in clinical practice. There also is little known about the effects of what is provided in the pump data, in correlation to quality-of-life following dLVAD implantation. Therefore, the purpose of this study is to prospectively analyze normal and abnormal pump data through pump operations such as suction events, low flow alarms as well as other adventitious alarms, PI events and power cable disconnects greater than 20 seconds, from the HeartMate 3 ® dLVAD in order to clinically correlate this data to quality of life, frailty and other various medical conditions and adverse events as defined by the Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs). This will be achieved t…

This description comes directly from the study's public registry record.

Talk to the study team

Sarah E Schroeder, PhD MSN RN  ·  402-937-3595  ·  sarah.schroeder@vadcoordinator.org

Thomas Schloglhofer, MSc  ·  +43 650 7119129  ·  thomas.schloeglhofer@meduniwien.ac.at

Always discuss trial participation with your own doctor first.

Locations (7)

UCSFSan Francisco, California, United StatesRecruiting
University of FloridaGainesville, Florida, United StatesRecruiting
University of ChicagoChicago, Illinois, United StatesRecruiting
University of Kansas Medical CenterKansas City, Kansas, United StatesActive Not Recruiting
Mayo Clinic-RochesterRochester, Minnesota, United StatesRecruiting
MUSCCharleston, South Carolina, United StatesActive Not Recruiting
University of UtahSalt Lake City, Utah, United StatesActive Not Recruiting

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Source record: clinicaltrials.gov/study/NCT06039176