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Study identifier: NCT06036004 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Oxytocin Substitution Therapy in Patients With Central Diabetes Insipidus

Condition: Central Diabetes Insipidus (cDI)  ·  Sponsor: University Hospital, Basel, Switzerland

PhasePhase 2
Planned participants112
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This randomized, placebo-controlled, double-blind trial aims to investigate intranasal OXT as a novel therapeutical option in central diabetes insipidus (cDI) to improve psychological symptoms and socio-emotional functioning. Optionally, patients can present for additional assessments in sub-studies: * fMRI sub-study at day 14 (± 2 days) (one additional visit) * Social-stress sub-study at day 14 (± 2 days) (one additional visit)

This description comes directly from the study's public registry record.

Talk to the study team

Mirjam Christ-Crain, Prof. Dr. med.  ·  +41 61 328 70 80  ·  mirjam.christ-crain@ubs.ch

Always discuss trial participation with your own doctor first.

Locations (3)

Charité University Medical Center BerlinBerlin, GermanyRecruiting
Erasmus University Medical Center RotterdamRotterdam, NetherlandsRecruiting
University Hospital Basel, Department of Endocrinology, Diabetes & MetabolismBasel, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT06036004