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Study identifier: NCT06035120 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema

Condition: Emphysema, Pulmonary · Emphysema or COPD  ·  Sponsor: Pulmonx Corporation

PhaseNA
Planned participants200
Who can joinAll sexes, 40 Years to 80 Years
Healthy volunteersNo

About this study

This is a prospective, open-label, multi-center, single-arm study planned to enroll 200 subjects with heterogeneous emphysema and collateral ventilation (CV) in the target lobe. Subjects will undergo instillation of AeriSeal Foam in the target lobe and subsequent assessment of CV status using Chartis Pulmonary Assessment System. Subjects with CV- status will then undergo placement of Zephyr Valve in the target lobe for bronchoscopic lung volume reduction (BLVR) and be followed for 24 months.

This description comes directly from the study's public registry record.

Talk to the study team

Christina Kutzavitch, PhD  ·  +1 650-216-0134  ·  ckutzavitch@pulmonx.com

Marie Barrigar  ·  marie.barrigar@pulmonx.com

Always discuss trial participation with your own doctor first.

Locations (36)

Banner University Medical CenterPhoenix, Arizona, United StatesRecruiting
Saint Francis Hospital and Medical Center (Trinity Health of New England)Hartford, Connecticut, United StatesRecruiting
Orlando HealthOrlando, Florida, United StatesRecruiting
Northwestern UniversityChicago, Illinois, United StatesRecruiting
University of Chicago Medical CenterChicago, Illinois, United StatesRecruiting
OSF Saint Francis Medical CenterPeoria, Illinois, United StatesRecruiting
Beth Israel Deaconess Medical CenterBoston, Massachusetts, United StatesRecruiting
Brigham Lung CenterBoston, Massachusetts, United StatesWithdrawn
Henry Ford HospitalDetroit, Michigan, United StatesRecruiting
Cleveland VA NortheastCleveland, Ohio, United StatesWithdrawn
Penn MedicinePhiladelphia, Pennsylvania, United StatesRecruiting
Temple UniversityPhiladelphia, Pennsylvania, United StatesRecruiting

+ 24 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06035120