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Study identifier: NCT06033703 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment

Condition: Rhegmatogenous Retinal Detachment · Proliferative Vitreoretinopathy  ·  Sponsor: Massachusetts Eye and Ear Infirmary

PhasePhase 1/Phase 2
Planned participants48
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

This study has two main objectives. The first objective is to study the pharmacokinetics of topical netarsudil administration in the posterior segment of the eye, where netarsudil must exert its effect in order to prevent formation of tractional membranes. The second objective is to assess the safety profile of topical netarsudil in the pre- and post-operative periods. A secondary objective of the study is to begin to assess signs of efficacy in preventing formation of tractional membranes post-operatively.

This description comes directly from the study's public registry record.

Talk to the study team

Leo Kim, MD, PhD  ·  6175237900  ·  Leo_Kim@meei.harvard.edu

Center for Clinical Research Operations (CCRO)  ·  6175736060

Always discuss trial participation with your own doctor first.

Locations (1)

Mass Eye and EarBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06033703