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Study identifier: NCT06032559 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment

Condition: Opioid Use · Pain  ·  Sponsor: Rutgers, The State University of New Jersey

PhasePhase 3
Planned participants450
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This hybrid implementation-effectiveness trial will evaluate Mindfulness-Oriented Recovery Enhancement (MORE) for patients with opioid use disorder receiving methadone treatment (MT). The investigators will also assess barriers and facilitators to integrating MORE into methadone treatment, and evaluate the impact of a sustainable train-the-trainer model on provider burden, intervention fidelity, intervention engagement, and outcomes. Participants will be assigned to a higher intensity MORE implementation strategy, a minimal intensity implementation strategy consisting of a simple, scripted mindfulness practice (SMP) extracted from the MORE treatment manual with minimal training and feedback and no supervision, or methadone treatment as usual (TAU). We aim to: * Examine barriers and facilitators to the implementation of MORE and SMP in MT and evaluate strategies for optimizing training, fidelity, and engagement. * Evaluate the effectiveness and treatment fidelity of a higher intensity MORE implementation strategy versus a lower intensity, scripted mindfulness practice (SMP) implementation strategy as an adjunct to methadone TAU or methadone TAU, only. Outcomes include opioid and other drug use, craving, MT discontinuation, depression, anxiety, and physical pain (secondary outcomes) than patients randomized to TAU.

This description comes directly from the study's public registry record.

Talk to the study team

Nina Cooperman, PsyD  ·  732-235-8569  ·  cooperna@rwjms.rutgers.edu

Eric Garland, PhD  ·  801-581-3826  ·  eric.garland@socwk.utah.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Rutgers Robert Wood Johnson Medical SchoolNew Brunswick, New Jersey, United StatesRecruiting
University of UtahSalt Lake City, Utah, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06032559