Condition: Elderly · Cancer Surgery · Dexmedetomidine · Sponsor: Peking University First Hospital
Along with aging population, cancer incidence and mortality are increasing. However, despite advances in oncology and surgery, long-term survival of cancer patients is far from optimal. Dexmedetomidine is a highly selective alpha 2 adrenergic receptor agonist with sedative, analgesic, and anxiolytic effects. Studies showed that perioperative use of dexmedetomidine reduces delirium and some non-delirium complications after surgery. In long-term follow-up studies of older patients who, for other reasons, were randomized to receive either dexmedetomidine or placebo during intra- or postoperative period, dexmedetomidine use was associated with improved long-term survival. This multicenter randomized trial aims to investigate the effect of perioperative dexmedetomidine on long-term outcomes in older patients undergoing cancer surgery.
This description comes directly from the study's public registry record.
Dong-Xin Wang, MD,PhD · 8610 83572784 · wangdongxin@hotmail.com
Jia-Hui Ma, PhD · 8610 83575138 · mjh@bjmu.edu.cn
Always discuss trial participation with your own doctor first.
| The First Affiliated Hospital of China University of Science and Technology | Hefei, Anhui, China | Recruiting |
| The First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital) | Hefei, Anhui, China | Recruiting |
| Peking University First Hospital | Beijing, Beijing Municipality, China | Recruiting |
| Tsinghua University Yuquan Hospital | Beijing, Beijing Municipality, China | Recruiting |
| Cancer Hospital Chinese Academy of Medical Sciences | Beijing, Beijing Municipality, China | Recruiting |
| The First Affiliated Hospital of Army Medical University (Southwest Hospital) | Chongqing, Chongqing Municipality, China | Recruiting |
| Fujian Provincial Hospital | Fuzhou, Fujian, China | Recruiting |
| The First Affiliated Hospital of Fujian Medical University | Fuzhou, Fujian, China | Recruiting |
| Fujian Medical University Union Hospital | Fuzhou, Fujian, China | Not Yet Recruiting |
| Jinjiang City Hospital (Shanghai Sixth People's Hospital, Fujian Hospital) | Jinjiang, Fujian, China | Recruiting |
| Guangdong General Hospital | Guangzhou, Guangdong, China | Recruiting |
| Peking University Shenzhen Hospital | Shenzhen, Guangdong, China | Recruiting |
+ 27 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06030804