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Study identifier: NCT06030349 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea in Children With Down Syndrome

Condition: Obstructive Sleep Apnea · Down Syndrome · Quality of Life  ·  Sponsor: Children's Health Ireland

PhaseN/A
Planned participants200
Who can joinAll sexes, 6 Months to 16 Years
Healthy volunteersNo

About this study

The goal of this observational study is to learn about the use of non-invasive ventilation for treatment of obstructive sleep apnoea syndrome in children with Down Syndrome. The main questions it aims to answer are: * What is the impact of non-invasive ventilation on sleep behaviours and quality of life? * What barriers are faced by children and their families in establishing tolerance to non-invasive ventilation? Participants will be asked to complete questionnaires before and after starting treatment. Researchers will compare this data with the results of sleep studies and non-invasive ventilator downloads recorded as part of standard medical care. A sub-group of up to 20 participants will be invited to take part in 45-60 minute interviews exploring expectations, experiences and barriers encountered during non-invasive ventilation therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Roy G Stone  ·  0035314282626  ·  refreshed@olchc.ie

Always discuss trial participation with your own doctor first.

Locations (6)

Trinity College DublinDublin, IrelandRecruiting
Children's Health IrelandDublin, IrelandRecruiting
Royal Belfast Hospital for Sick ChildrenBelfast, United KingdomNot Yet Recruiting
Birmingham Children's HospitalBirmingham, United KingdomNot Yet Recruiting
Royal Hospital for Children & Young PeopleEdinburgh, United KingdomNot Yet Recruiting
Southampton Children's HospitalSouthampton, United KingdomNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06030349