Condition: Estrogen Receptor-Positive Breast Carcinoma · Sponsor: Mayo Clinic
This phase II trial tests how well Reishi mushroom extract works in treating fatigue and/or joint/muscle pain (arthralgias/myalgias) in patients with breast cancer on aromatase inhibitors. Fatigue and arthralgias/myalgias are common symptoms in breast cancer patients taking aromatase inhibitors (AI). Given the long duration of AI treatment for some women (up to 10 years), these symptoms can significantly impact quality of life and premature discontinuation of AIs, a beneficial medication. Reishi mushrooms are among several medicinal mushrooms that have been used for hundreds of years, mainly in Asian countries, to help enhance the immune system, reduce stress, improve sleep, and lessen fatigue. Reishi mushroom extracts have not been studied explicitly for treatment-induced arthralgias/myalgias, but have been shown to improve quality of life, muscular strength, pain, and flexibility. Information from this study may help researchers determine the effect of Reishi mushroom extract on fatigue and arthralgias/myalgias in breast cancer patients receiving an AI.
This description comes directly from the study's public registry record.
Clinical Trials Referral Office · 855-776-0015 · mayocliniccancerstudies@mayo.edu
Always discuss trial participation with your own doctor first.
| Mayo Clinic Health System in Albert Lea | Albert Lea, Minnesota, United States | Recruiting |
| Essentia Health Baxter Clinic | Baxter, Minnesota, United States | Recruiting |
| Sanford Joe Lueken Cancer Center | Bemidji, Minnesota, United States | Recruiting |
| Essentia Health Saint Joseph's Medical Center | Brainerd, Minnesota, United States | Recruiting |
| Essentia Health Deer River Clinic | Deer River, Minnesota, United States | Recruiting |
| Essentia Health Saint Mary's - Detroit Lakes Clinic | Detroit Lakes, Minnesota, United States | Recruiting |
| Essentia Health Cancer Center | Duluth, Minnesota, United States | Recruiting |
| Essentia Health Ely Clinic | Ely, Minnesota, United States | Recruiting |
| Essentia Health Fosston | Fosston, Minnesota, United States | Recruiting |
| Fairview Grand Itasca Clinic & Hospital | Grand Rapids, Minnesota, United States | Recruiting |
| Essentia Health Hibbing Clinic | Hibbing, Minnesota, United States | Recruiting |
| Fairview Range Medical Center | Hibbing, Minnesota, United States | Recruiting |
+ 11 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06028022