● Recruiting

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

Condition: Solid Tumors With HRAS Alterations · Non Small Cell Lung Cancer (NSCLC) · Colorectal Cancer (CRC) · Sponsor: Kura Oncology, Inc.

PhasePhase 1

Planned participants300

Who can joinAll sexes, 18 Years to no upper limit

Healthy volunteersNo

About this study

This first-in-human (FIH) dose-escalation and dose-validation/expansion study will assess KO-2806, a farnesyltransferase inhibitor (FTI), as a monotherapy and in combination, in adult patients with advanced solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Kura Medical Information · 844-KURAONC (844-587-2662) · medinfo@kuraoncology.com

Always discuss trial participation with your own doctor first.

Locations (38)

Mayo Clinic Comprehensive Cancer Center	Phoenix, Arizona, United States	Recruiting
University of Arizona	Tucson, Arizona, United States	Recruiting
University of Southern California	Los Angeles, California, United States	Recruiting
Cedars-Sinai Medical Center	Los Angeles, California, United States	Recruiting
UCLA Department of Medicine	Los Angeles, California, United States	Recruiting
Sarah Cannon Research Institute at HealthONE	Denver, Colorado, United States	Recruiting
AdventHealth Celebration	Celebration, Florida, United States	Recruiting
Mayo Clinic Comprehensive Cancer Center	Jacksonville, Florida, United States	Recruiting
Florida Cancer Specialists	Sarasota, Florida, United States	Recruiting
University of Iowa Hospitals & Clinics	Iowa City, Iowa, United States	Recruiting
Dana-Farber Cancer Institute	Boston, Massachusetts, United States	Recruiting
Henry Ford Health System	Detroit, Michigan, United States	Recruiting

+ 26 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06026410