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Study identifier: NCT06023186 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Mavacamten Treatment on Coronary Flow Reserve in oHCM

Condition: Obstructive Hypertrophic Cardiomyopathy  ·  Sponsor: Michael Ayers

PhaseN/A
Planned participants20
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

The goal of this observational study is to measure the effect of mavacamten treatment on blood flow in the heart muscle (myocardium) in patients with obstructive hypertrophic cardiomyopathy. The main question it aims to answer is: • Does mavacamten treatment improve blood flow in the heart muscle? Participants will take mavacamten at the direction of their treating physician. Participants will complete 2 myocardial Positron Emission Tomography and Computed Tomography (PET-CT) scans. The first scan will be completed before participants start taking mavacamten. The scan will be repeated after 12 months of mavacamten treatment.

This description comes directly from the study's public registry record.

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Locations (1)

University of VirginiaCharlottesville, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06023186