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Study identifier: NCT06017869 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Evaluate the Safety and Therapeutic Effects of a Single Intravenous Infusion (IV) of Autologous CD34+ Cells Enriched With Allogenic Placenta-derived Mitochondria in Patients With a Diagnosis of Pearson Syndrome (PS)

Condition: Mitochondrial Diseases · Pearson Syndrome  ·  Sponsor: Minovia Therapeutics Ltd.

PhasePhase 2
Planned participants6
Who can joinAll sexes, 1 Year to 18 Years
Healthy volunteersNo

About this study

Primary Mitochondrial diseases are a clinically and genetically heterogeneous group of disorders caused by mutations in genes encoded by nuclear Deoxyribonucleic Acid (DNA) or by mutations and/or deletions in the mitochondrial DNA (mtDNA). While some mitochondrial disorders only affect a single organ (e.g., the eye in Leber hereditary optic neuropathy \[LHON\]), many involve multiple organs. Mitochondrial disorders may present at any age and a frequent feature is the increasing number of organs involved in the course of the disease. Minovia Therapeutics Ltd. ("Minovia") is a biotech company developing novel therapeutics based on its mitochondrial augmentation technology (MAT). MNV-201 is a cell therapy produced by MAT that consists of the participant's autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) enriched with allogeneic placental-derived mitochondria, manufactured in Minovia's GMP facility.

This description comes directly from the study's public registry record.

Talk to the study team

Lea Bensoussan, Msc  ·  + 972 586101291  ·  lea@minoviatx.com

Natalie Yivgi Ohana, PhD  ·  +972 54 5833727  ·  natalie@minoviatx.com

Always discuss trial participation with your own doctor first.

Locations (1)

Sheba Medical CenterRamat Gan, Israel, IsraelRecruiting

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Source record: clinicaltrials.gov/study/NCT06017869