Condition: Ovarian Cancer · Fallopian Tube Cancer · Primary Peritoneal Cancer · Sponsor: Hansoh BioMedical R&D Company
HS-20089 is an investigational antibody-drug conjugate (ADC) composed of a humanized IgG1 anti-B7-H4 monoclonal antibody conjugated to the topoisomerase I inhibitor payload via a protease-cleavable linker, with an average drug-to-antibody ratio of about 6. This is a phase 2, open-label, multi-center study to evaluate the efficacy, safety, pharmacokinetics (PK) and immunogenicity of HS-20089 as monotherapy in patients with recurrent or metastatic ovarian cancer and endometrial cancer.
This description comes directly from the study's public registry record.
Lingying Wu, MD · 010-87788996 · wulingying@csco.org.cn
Dawei Wu · 010-87788495 · cancergcp@163.com
Always discuss trial participation with your own doctor first.
| Anhui Provincial Cancer Hospital | Hefei, Anfei, China | Recruiting |
| Lingying Wu | Beijing, Beijing Municipality, China | Recruiting |
| Peking University Cancer Hospital | Beijing, Beijing Municipality, China | Recruiting |
| Chongqing University cancer Hospital | Chongqing, Chongqing Municipality, China | Suspended |
| Fujian Cancer Hospital | Fuzhou, Fujian, China | Recruiting |
| Sun Yat-Sen Memorial Hospital Sun Yat-Sen University | Guangzhou, Guangdong, China | Recruiting |
| Guangxi Cancer Hospital | Nanning, Guangxi, China | Recruiting |
| Hainan General Hospital | Haikou, Hainan, China | Recruiting |
| The fourth Hospital of Heibei Medical University | Shijiazhuang, Hebei, China | Recruiting |
| Harbin Medical University Cancer Hospital | Harbin, Heilongjiang, China | Recruiting |
| Henan Cancer Hospital | Zhengzhou, Henan, China | Recruiting |
| Hubei Cancer University | Wuhan, Hubei, China | Recruiting |
+ 16 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06014190