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Study identifier: NCT06012695 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

NBM-BMX Administered Orally to Patients With Solid Tumors or Newly Diagnosed Glioblastoma

Condition: Malignant Neoplasm · Malignant Neoplasm of Brain  ·  Sponsor: Novelwise Pharmaceutical Corporation

PhasePhase 1/Phase 2
Planned participants79
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

NBM-BMX is an orally available new chemical entity to inhibit histone deacetylases 8 (HDAC8) activity specifically, being developed as a potential anti-cancer therapeutic by NatureWise. This study aims to evaluate the safety, pharmacokinetics, and preliminary efficacy of NBM-BMX as monotherapy in subjects with advanced solid tumors or combination with the standard of care treatment in subjects with newly diagnosed glioblastoma.

This description comes directly from the study's public registry record.

Talk to the study team

Chia-Chung Hou, Ph.D.  ·  +886 2 26559109  ·  alison.hou@novelwisepharma.com

Karis Chiang  ·  +886 2 27891060  ·  karis.chiang@effpha.com

Always discuss trial participation with your own doctor first.

Locations (4)

Kaohsiung Medical University Chung-Ho Memorial HospitalKaohsiung City, TaiwanNot Yet Recruiting
Taichung Veterans General HospitalTaichung, TaiwanRecruiting
Koo Foundation Sun Yat-Sen Cancer CenterTaipei, TaiwanRecruiting
Linkou Chang-Gung Memorial HospitalTaoyuan City, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT06012695