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Study identifier: NCT06012227 Synced from ClinicalTrials.gov · July 29, 2026
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Assessment Metabolic Flexibility in Middle-aged Individuals: The Nutritional Impact of Cheese Consumption

Condition: Metabolism · Nutrition  ·  Sponsor: University of Cagliari

PhaseNA
Planned participants105
Who can joinAll sexes, 45 Years to 65 Years
Healthy volunteersYes

About this study

The aim of the study will be to evaluate the impact of consumption of meat and dairy products from extensive or intensive farming on apparently healthy individuals aged between 45 and 65 years, a stage of life associated with reduced metabolic flexibility and changes in lipid metabolism. The study will analyze: 1. The transcription factor PPAR-α determined by the gene expression of PPAR-α in white blood cells, variations in circulating fatty acid metabolism, and the endocannabinoid system determined by circulating analysis of N-acylethanolamine (NAE), and 2-monoacylglycerols (2-MG); 2. Metabolic flexibility, determined by indirect calorimetry in fasting condition during an incremental exercise; 3. Body composition, determined by bioimpedance analysis, waist circumference, and waist-to-hip ratio.

This description comes directly from the study's public registry record.

Talk to the study team

Sebastiano Banni  ·  070-6754128  ·  banni@unica.it

Always discuss trial participation with your own doctor first.

Locations (1)

University of CagliariMonserrato, Cagliari, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06012227