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Study identifier: NCT06011876 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

BioFLO for Respiratory Recovery in SCI

Condition: Spinal Cord Injuries  ·  Sponsor: University of Florida

PhaseNA
Planned participants62
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

Acute intermittent hypoxia (AIH) involves brief (1 min), repeated episodes (\~15) of breathing low oxygen air to stimulate spinal neuroplasticity. Animal and human studies show that AIH improves motor function after spinal cord injury, particularly with slightly increased carbon dioxide (hypercapnic AIH; AIHH) and task-specific training. Using a double blind cross-over design, the study will test whether AIHH improves breathing more than AIH and whether specific genetic variations are related to individuals' intervention responses.

This description comes directly from the study's public registry record.

Talk to the study team

Emily J Fox, PT, MHS, PhD  ·  904-742-2500  ·  ejfox@phhp.ufl.edu

Hannah Snyder, M.S.  ·  904-345-6910  ·  Hannah.snyder@brooksrehab.org

Always discuss trial participation with your own doctor first.

Locations (1)

Brooks RehabilitationJacksonville, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06011876