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Study identifier: NCT06009276 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status

Condition: Heart Failure, Systolic · Heart Failure, Diastolic · Peripheral Arterial Disease  ·  Sponsor: University of Virginia

PhaseN/A
Planned participants70
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of the study is to determine associations between fitness status, bacteria in the mouth, and the blood flow to muscle. This study is trying to find out if fitness status impacts the bacteria that are present in the oral microbiome (environment in the mouth) or the ability of the body to send blood to the skeletal muscle. Participants will complete all or some of the following: * A mouth swab to assess the bacteria in their mouths. * Produce a saliva sample into a tube. * Cycle on a bike until you reach maximum effort. * Undergo blood draws * Wear a 24-hour non-invasive device that monitors blood pressure. * Drink 70mL (1/3 of a cup) of concentrated beetroot juice once

This description comes directly from the study's public registry record.

Talk to the study team

Casey C Derella, PhD  ·  6092476377  ·  bxg7vn@virginia.edu

Macy E Stahl, B.S.E.d  ·  5719698323  ·  mes4hm@virginia.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UVA Student Health and Wellness BuildingCharlottesville, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06009276