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Study identifier: NCT06008106 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Comparing Tunlametinib Capsules and Combination Chemotherapy in Advanced NRAS-mutant Melanoma

Condition: Melanoma  ·  Sponsor: Shanghai Kechow Pharma, Inc.

PhasePhase 3
Planned participants165
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a multicenter, two-arm, open-label, randomized controlled phase III clinical trial to evaluate the efficacy and safety of tunlametinib capsule in comparison with the combination chemotherapy of investigator's choice in advanced melanoma patients with NRAS mutation who have received immunotherapy before. Subjects were stratified according to the baseline lactate dehydrogenase level and chemotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Lixia Gong, Master  ·  15800569407  ·  gonglx@kechowpharma.com

Always discuss trial participation with your own doctor first.

Locations (1)

Beijing Cancer HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06008106