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Study identifier: NCT06007495 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Pilot Physiological Evaluation of an Investigational Mask with Expiratory Washout.

Condition: Acute Hypercapnic Respiratory Failure · Acute Hypoxemic Respiratory Failure  ·  Sponsor: Fisher and Paykel Healthcare

PhaseNA
Planned participants32
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this pilot randomized cross-over study is to compare the effect of a full-face mask with expiratory washout to a conventional full face mask on non-invasive ventilation (NIV) in patients with acute hypercapnic, and acute hypoxemic, respiratory failure. The main questions it aims to answer are: * Does a mask with expiratory washout improve minute ventilation in patients using non-invasive ventilation compared with a conventional single-limb NIV mask * How does a mask with expiratory washout affect respiratory variables compared with a dual-limb NIV mask. Participants already prescribed NIV will undergo 3 arms of the investigation in a randomized order: * Single-limb NIV with investigation mask (with expiratory washout) * Single-limb NIV with conventional mask * Dual-limb NIV with conventional mask

This description comes directly from the study's public registry record.

Talk to the study team

James Miller  ·  +64273032944  ·  jamie.miller@fphcare.co.nz

Always discuss trial participation with your own doctor first.

Locations (2)

Centre hospitalier de l'Université de Montréal (CHUM)Montreal, Quebec, CanadaRecruiting
Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ)Québec, Quebec, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06007495