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Study identifier: NCT06006403 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety and Efficacy of CD123-targeted CAR-NK for Relapsed/Refractory Acute Myeloid Leukemia or Blastic Plasmacytoid Dendritic Cell Neoplasm

Condition: Acute Myeloid Leukemia · Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) · Relapse Leukemia  ·  Sponsor: Chongqing Precision Biotech Co., Ltd

PhasePhase 1/Phase 2
Planned participants36
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study is a single-arm, open-label, dose-escalating + dose-expansion clinical study, aiming to evaluate the safety and efficacy of targeting CD123 CAR-NK cell preparations in Relapsed/refractory acute myeloid leukemia (AML) or blastocytic plasmacytoid dendritic cell neoplasm (BPDCN). The pharmacokinetic characteristics of CAR-NK cell preparations for the treatment of patients with Relapsed/refractory acute myeloid leukemia or blastocytic plasmacytoid dendritic cell neoplasm were obtained and the recommended dose.

This description comes directly from the study's public registry record.

Talk to the study team

Jia Wei, M.D  ·  13986102084  ·  jiawei@tjh.tjmu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Shanxi Bethune HospitalTaiyuan, Shanxi, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06006403