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Study identifier: NCT06001788 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Condition: AML · AML With Mutated NPM1 · Hematologic Malignancy  ·  Sponsor: Kura Oncology, Inc.

PhasePhase 1
Planned participants171
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The safety, tolerability, and antileukemic response of ziftomenib in combination with standard of care treatments for patients with relapsed/refractory acute myeloid leukemia will be examined with the following agents: FLAG-IDA, low-dose cytarabine, and gilteritinib.

This description comes directly from the study's public registry record.

Talk to the study team

Kura Medical Information  ·  844-KURAONC (844-587-2662)  ·  medinfo@kuraoncology.com

Always discuss trial participation with your own doctor first.

Locations (45)

Banner MD Anderson Cancer CenterGilbert, Arizona, United StatesRecruiting
USC Norris Comprehensive Cancer CenterLos Angeles, California, United StatesRecruiting
UCLA Health - Bowyer Oncology CenterLos Angeles, California, United StatesRecruiting
UC Irvine Health Chao Family Comprehensive Cancer CenterOrange, California, United StatesRecruiting
University of California San FranciscoSan Francisco, California, United StatesRecruiting
Colorado Blood Cancer InstituteDenver, Colorado, United StatesRecruiting
Smilow Cancer Hospital at Yale New HavenNew Haven, Connecticut, United StatesRecruiting
Emory Healthcare - The Emory ClinicAtlanta, Georgia, United StatesRecruiting
Georgia Cancer Center at Augusta UniversityAugusta, Georgia, United StatesRecruiting
Robert H. Lurie Comprehensive Cancer Center of Northwestern UniversityChicago, Illinois, United StatesRecruiting
Loyola University Medical CenterMaywood, Illinois, United StatesRecruiting
Simmons Cancer InstituteSpringfield, Illinois, United StatesWithdrawn

+ 33 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06001788