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Study identifier: NCT05993754 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Non-pharmacological Prevention of POD in Frailty Elderly Undergoing Elective Surgery Applied by Nursing Teams

Condition: Frail Elderly Syndrome · Primary Prevention · Postoperative Delirium  ·  Sponsor: Pontificia Universidad Catolica de Chile

PhaseNA
Planned participants400
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersNo

About this study

The increase in the population over 60 years of age who could receive surgery due to changes in life expectancy and advances in surgical and anesthetic techniques. Likewise, elderly people (EP) may have a higher risk of postoperative morbidity and mortality compared to young people, with frailty being one of the risk factors that increases adverse outcomes in this period and increases the probability of developing syndromes such as postoperative delirium (POD). Assessment of frailty in EP prior to surgery is not routine, so it is unknown how many frail and/or pre-frail EP undergo surgery in health care systems. There is an association between being frail and developing greater delirium and/or postoperative cognitive deficit, which in summary translates into an increase in perioperative morbidity and mortality. For the prevention of POD, there are pharmacological and non-pharmacological measures that seek to promote orientation with respect to their environment and make it as familiar as possible, stimulate early aspects of memory and thinking skills, as well as promote sleep using environmental hygiene measures. In Chile, protocols of non-pharmacological measures have been proposed by occupational therapy teams, which have had positive results in reducing POD in frail elderly patients. These measures are temporal-spatial reorientation, physical mobilization, correction of sensory deficits, environmental management, sleep protocol, and reduction of anticholinergic drugs wi…

This description comes directly from the study's public registry record.

Talk to the study team

Victor Contreras, MSN  ·  +56955049217  ·  vecontre@uc.cl

Karen Azagra, BcS  ·  +56955049217  ·  karen.azagra@uc.cl

Always discuss trial participation with your own doctor first.

Locations (1)

Pontificia Universidad Catolica de ChileSantiago, Santiago Metropolitan, ChileRecruiting

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Source record: clinicaltrials.gov/study/NCT05993754