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Study identifier: NCT05993234 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of Trastuzumab DeRuxtecan for Patients With Advanced HER2-pOsitive GaStric or GastroesoPhageal Junction AdEnocarcinoma Who Have Received a PrIor Trastuzumab-based Regimen Accompanied by a Disease RegistrY of Patients Treated With Conventional Therapies (PROSPERITY)

Condition: HER2-positive Advanced Gastric Cancer · HER2-positive Gastroesophageal Junction Adenocarcinoma  ·  Sponsor: Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

PhaseN/A
Planned participants257
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Trastuzumab deruxtecan (T-DXD) as monotherapy is indicated for the treatment of adult patients with advanced HER2-positive advanced gastric or gastroesophageal junction (GEJ) adenocarcinoma who have received a prior trastuzumab-based regimen. This study will assess the effectiveness of T-DXd, patient demographic and clinical characteristics, and treatment patterns in patients with advanced HER2-positive advanced gastric or GEJ adenocarcinoma.

This description comes directly from the study's public registry record.

Talk to the study team

Contact for Clinical Trial Information  ·  908-992-6400  ·  CTRinfo@dsi.com

Always discuss trial participation with your own doctor first.

Locations (76)

KABEG Klinikum Klagenfurt am Wörthersee - Landeskrankenanstalten LKHKlagenfurt, AustriaWithdrawn
Ordensklinikum Linz GmbH Barmherzige SchwesternLinz, AustriaActive Not Recruiting
Universitätsklinikum St. Pölten - LilienfeldSankt Pölten, AustriaWithdrawn
Medizinische Universität WienVienna, AustriaActive Not Recruiting
St. Josef Krankenhaus GmbH Ein Unternehmen der Vinzenz GruppeVienna, AustriaWithdrawn
Klinik Ottakring, Wilhelminenspital der Stadt WienVienna, AustriaWithdrawn
Kepler UniversitätsklinikumWels, AustriaActive Not Recruiting
Landesklinikum Wiener NeustadtWiener Neustadt, AustriaActive Not Recruiting
Krankenhaus St. Vinzenz in ZamsZams, AustriaActive Not Recruiting
OLV Hospital AalstAalst, BelgiumActive Not Recruiting
Imelda vzwBonheiden, BelgiumWithdrawn
HUB institut Jules BordetBrussels, BelgiumWithdrawn

+ 64 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05993234