Condition: Alcohol Use Disorder (AUD) · Alcoholism · Substance Use Disorders · Sponsor: Charite University, Berlin, Germany
Individuals with substance use disorders (SUD) have to cope with drug-related cues and contexts, which can affect instrumental drug seeking as shown with Pavlovian to instrumental transfer (PIT) paradigms in animals and humans. The investigators aimed to investigate the impact of acute and chronic stress on Pavlovian-to-instrumental transfer (PIT), how PIT it is associated with cognitive control abilities and whether such effects predict losing vs. regaining control in subjects with AUD. Moreover, the investigators aimed to develop a novel full transfer task that assesses both, general and specific PIT to investigate whether specific PIT differs between alcohol use disorder (AUD) and control subjects.
This description comes directly from the study's public registry record.
Andreas Heinz, Prof., MD, PhD · 0049 30 450 517 001 · andreas.heinz@charite.de
Maximilian Pilhatsch, MD, PhD · 0049 (351) 458 19312 · max.pilhatsch@uniklinikum-dresden.de
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| Charite - Universitätsmedizin Berlin | Berlin, Germany | Recruiting |
| Technische Universität Dresden | Dresden, Germany | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05992272