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Study identifier: NCT05991817 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Sevoflurane General Anesthetic and Spatial Memory in Humans

Condition: Spatial Memory Disorder  ·  Sponsor: University of Chile

PhaseN/A
Planned participants22
Who can joinAll sexes, 30 Years to 50 Years
Healthy volunteersNo

About this study

The goal of this observational study is to learn about the effect of general anesthetic on spatial memory in adults who will undergo to an elective surgery. The main question it aims to answer is: • A surgical event under general anesthesia with sevoflurane transiently impairs spatial memory in humans and induces an increase in inflammatory cytokines. Participants will perform a virtual maze test and plasma samples will be taken before and after surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Antonello Penna, MD, PhD  ·  +56956766623  ·  apenna@uchile.cl

Khaleed Etchegaray  ·  +56973310929  ·  khaleed.etchegaray@gmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

Centro de Investigación Cínica Avanzada (CICA), Hospital Clinico de la Universidad de ChileSantiago, RM, ChileRecruiting
Hospital Clinico de la Universidad de ChileSantiago, RM, ChileRecruiting

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Source record: clinicaltrials.gov/study/NCT05991817