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Study identifier: NCT05991453 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

Condition: Surgery-Complications · Anesthesia Complication · Anesthesia Awareness  ·  Sponsor: Washington University School of Medicine

PhaseNA
Planned participants13000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The investigators will conduct a 13,000-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (ii) whether TIVA confers no more than a small (0.2 %) increased risk of intraoperative awareness than INVA in patients undergoing both outpatient and inpatient surgeries

This description comes directly from the study's public registry record.

Talk to the study team

Laura Swisher  ·  314-286-1024  ·  goodl@wustl.edu

Sherry McKinnon  ·  314-286-1024  ·  smckinnon@wustl.edu

Always discuss trial participation with your own doctor first.

Locations (20)

University of Arkansas for Medical Sciences (UAMS)Little Rock, Arkansas, United StatesRecruiting
University of California San FranciscoSan Francisco, California, United StatesRecruiting
Stanford UniversityStanford, California, United StatesNot Yet Recruiting
Yale School of MedicineNew Haven, Connecticut, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
Brigham & Women'sBoston, Massachusetts, United StatesRecruiting
University of MichiganAnn Arbor, Michigan, United StatesRecruiting
Henry Ford HealthDetroit, Michigan, United StatesRecruiting
Washington University School of MedicineSt Louis, Missouri, United StatesRecruiting
Dartmouth Hitchcock Medical CenterLebanon, New Hampshire, United StatesRecruiting
NYU LangoneNew York, New York, United StatesRecruiting
Weill Cornell MedicineNew York, New York, United StatesRecruiting

+ 8 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05991453