← Eichor
Study identifier: NCT05990790 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Effect of Desflurane Versus Sevoflurane Versus Propofol on Postoperative Delirium

Condition: Postoperative Delirium · Major Noncardiac Surgery · Postoperative Cognitive Dysfunction  ·  Sponsor: Medical University of Vienna

PhasePhase 4
Planned participants1332
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersNo

About this study

Patients over the age of 65 years are at increased risk for developing delirium after noncardiac surgeries, resulting in increased morbidity and mortality. The prevention of postoperative delirium has been classified as a public health priority. However, so far data regarding possible intraoperative interventions to reduce the incidence of postoperative delirium is very scarce. Due to the more rapid wash-in and wash-out times of desflurane as compared to sevoflurane or propofol it seems reasonable that desflurane might be beneficial for the prevention of postoperative delirium. Therefore, we evaluate the effect of maintenance of anesthesia using desflurane, sevoflurane or propofol on postoperative delirium in elderly patients undergoing moderate- to high-risk major noncardiac surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Alexander Taschner, MD  ·  0043 1 40400  ·  alexander.taschner@meduniwien.ac.at

Always discuss trial participation with your own doctor first.

Locations (2)

Medical University of InnsbruckInnsbruck, AustriaRecruiting
Medical University of ViennaVienna, AustriaRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05990790