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Study identifier: NCT05988632 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Intranasal Insulin for Treatment of Alcohol Use Disorder

Condition: Alcohol Use Disorder  ·  Sponsor: Brown University

PhasePhase 1/Phase 2
Planned participants40
Who can joinAll sexes, 21 Years to no upper limit
Healthy volunteersNo

About this study

This is a randomized controlled trial (RCT), within-subject, crossover, double-blind, placebo-controlled in non-treatment-seeking individuals with Alcohol Use Disorder (AUD) (N=40, 50% female) randomized to IN insulin or placebo. In a bar laboratory setting, randomized participants will receive a single dose of IN insulin (80IU) or an IN matched placebo (0.9% Saline). Participants will undergo a cue-reactivity paradigm followed by an alcohol challenge that includes an alcohol drink designed to raise the breath alcohol content (BrAC) to 0.08g/dL.

This description comes directly from the study's public registry record.

Talk to the study team

Carolina L Haass-Koffler  ·  4155191385  ·  carolina_haass-koffler@brown.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Brown UniversityProvidence, Rhode Island, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05988632