Condition: Hemophilia A · Sponsor: Hoffmann-La Roche
WP44714 is a Phase I/II, open-label, non-randomized, global, multicenter trial consisting of two parts: * Part 1 is a multiple-ascending dose (MAD) study in adult and adolescent male participants with severe or moderate hemophilia A with or without factor VIII (FVIII) inhibitors. * Part 2 is a multiple-dose study in pediatric male participants with severe or moderate hemophilia A with or without FVIII inhibitors. The overall aim of the study is to investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and efficacy of NXT007.
This description comes directly from the study's public registry record.
Reference Study ID Number: WP44714 https://forpatients.roche.com/ No attachments to email below. · 888-662-6728 (U.S. Only) · global-roche-genentech-trials@gene.com
Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry
Always discuss trial participation with your own doctor first.
| UC Davis Cancer Center | Sacramento, California, United States | Recruiting |
| Georgetown Uni Medical Center | Washington D.C., District of Columbia, United States | Withdrawn |
| Indiana Hemophilia & Thrombosis center | Indianapolis, Indiana, United States | Recruiting |
| University of Iowa Hospitals and Clnics Dept of Pediatrics | Iowa City, Iowa, United States | Recruiting |
| British Columbia Children's Hospital | Vancouver, British Columbia, Canada | Recruiting |
| Hamilton Health Sciences Corporation | Hamilton, Ontario, Canada | Recruiting |
| IRCCS Ca' Granda Ospedale Maggiore Policlinico | Milan, Lombardy, Italy | Recruiting |
| Istituto Clinico Humanitas | Rozzano (MI), Lombardy, Italy | Recruiting |
| Auckland Cancer Trial Centre | Auckland, New Zealand | Recruiting |
| Uniwersyteckie Centrum Kliniczne | Gda?sk, Poland | Recruiting |
| Instytut Hematologii i Transfuzjologii | Warsaw, Poland | Recruiting |
| Hospital Sant Joan de Deu | Esplugues de Llobregat, Barcelona, Spain | Recruiting |
+ 2 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05987449